Anti-NMDA Receptor Encephalitis: A Case of Atypical Acute Psychosis With Absence of Neurological Symptoms

Sarada BD, A Juares Rizal, KC Wong


Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an autoimmune disorder in which antibodies attack NMDA receptors at central neuronal synapses. Common symptoms include thought and perceptual disturbances, mood lability, disorganized behaviours, and personality change which can be overlooked and often entail psychiatrist as the primary team. The psychiatric manifestation is then accompanied by neurological symptoms which include abnormal movements and followed by autonomic instability. Misdiagnosis is frequent given the overlap of symptoms with psychiatric manifestations.

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Anti-NMDA Receptor Encephalitis; Psychosis; Behavioural Changes; Neurological Symptoms

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